0756 Validity of Self-reported Sleep in the Cancer Prevention Study – 3

Abstract Introduction Self-reported sleep measures are widely used in epidemiology research and may be influenced by a variety of factors, potentially introducing measurement error. We examined the one-year test/re-test concordance and validity of survey-assessed sleep duration. Methods The Activity Validation Sub Study (AVSS) included 751 participants of the Cancer Prevention Study-3 study to further investigate rest/activity cycles. Sleep duration was collected using three methods survey, Daysimeter device, and sleep diary. Survey-assessed sleep duration was collected in categorical and continuous formats. Selected participants (n=170) were asked to wear a device for seven consecutive days for two non-consecutive quarters and recorded sleep duration in sleep diaries for each night. Of the 170 study participants assigned a device, participants were excluded from the current study due to incomplete AVSS survey data, implausible device data, reported working night shift, insufficient days of device wear or diary entries, or reported less than 3 hours or greater than 14 hours of sleep for any of the sleep measures. We calculated concordance of pre- and post-survey sleep duration for both survey question using Spearman correlation. We used the method of triads to estimate the validity coefficient (VC) between the three sleep duration measurements in the present study and the “true” latent sleep duration measure, and bootstrapped 95% confidence intervals (95% CI). This was done for both survey-assessed sleep duration measures. Results A total of 117 participants were included in the study (53% male). Test-retest correlation for the pre- and post-survey showed strong and moderate correlations for sleep duration collected continuously and categorically, respectively. The VC for survey-assessed continuous sleep duration and the latent sleep duration was 0.83 (95% CI 0.72, 0.90) for weekday and 0.62 (95% CI 0.42, 0.78) for weekend. Performance of the VC was slightly weaker for survey-assessed categorical sleep duration (weekday VC=0.60 95% CI 0.45, 0.73; weekend VC=0.44 95% CI 0.29,0.61). Conclusion Performance of survey-assessed sleep duration as compared to device and diary measures varies based on how the question is asked and/or the response structure. Support (if any) The American Cancer Society funds the CPS-3 cohort. This work was supported through an unrestricted research grant from Sleep Number Corporation.