Income determines the impact of cash transfers on HIV/AIDS: cohort study of 22.7 million Brazilians

Andrea F. Silva,Ines Dourado,Iracema Lua,Gabriela S. Jesus, Nathalia S. Guimaraes, Gabriel A. S. Morais,Rodrigo V. R. Anderle,Julia M. Pescarini, Daiane B. Machado, Carlos A. S. T. Santos, Maria Y. Ichihara,Mauricio L. Barreto,Laio Magno, Luis E. Souza,James Macinko,Davide Rasella

NATURE COMMUNICATIONS(2024)

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摘要
Living with extremely low-income is an important risk factor for HIV/AIDS and can be mitigated by conditional cash transfers. Using a cohort of 22.7 million low-income individuals during 9 years, we evaluated the effects of the world's largest conditional cash transfer, the Programa Bolsa Familia, on HIV/AIDS-related outcomes. Exposure to Programa Bolsa Familia was associated with reduced AIDS incidence by 41% (RR:0.59; 95%CI:0.57-0.61), mortality by 39% (RR:0.61; 95%CI:0.57-0.64), and case fatality rates by 25% (RR:0.75; 95%CI:0.66-0.85) in the cohort, and Programa Bolsa Familia effects were considerably stronger among individuals of extremely low-income [reduction of 55% for incidence (RR:0.45, 95% CI:0.42-0.47), 54% mortality (RR:0.46, 95% CI:0.42-0.49), and 37% case-fatality (RR:0.63, 95% CI:0.51 -0.76)], decreasing gradually until having no effect in individuals with higher incomes. Similar effects were observed on HIV notification. Programa Bolsa Familia impact was also stronger among women and adolescents. Several sensitivity and triangulation analyses demonstrated the robustness of the results. Conditional cash transfers can significantly reduce AIDS morbidity and mortality in extremely vulnerable populations and should be considered an essential intervention to achieve AIDS-related sustainable development goals by 2030. Brazil has operated a conditional cash transfer program to support families living in precarious conditions since 2004. Here, the authors use linked administrative and health data to investigate the impacts of the program on HIV/AIDS-related outcomes, demonstrating strong positive associations.
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