PIPETS: A statistically robust, gene-annotation agnostic analysis method to study bacterial termination using 3'-end sequencing.

We present PIPETS, an R package available on Bioconductor that provides a novel analysis approach to study 3'-end sequencing data. PIPETS statistically robust, gene-annotation agnostic methodology identified more significant 3'-end termination signal across a wider range of genomic contexts than existing analysis tools. PIPETS provides a broadly applicable platform to compare data sets across different organisms.