Hematobiochemical, antioxidant, and lipid alterations in mice feed with thermally oxidized coconut oil

In the present study, the effects of recycled oxidized coconut oil were assessed on hematobiochemical, antioxidant and cardiac markers in albino mice. In all, 24 mice were divided into three groups: group I, II, and III; animals in each group received a normal diet as well as fresh and deep-oxidized coconut oil. The outcomes demonstrated that group III mice fed with thermally oxidized coconut oil revealed a significant alteration in the form of decreased count, hemoglobin (Hb), Hb concentration, mean corpuscular hemoglobin, and hematocrit (HCT) (p > 0.05). Likewise, levels of triglyceride, cholesterol, and low-density lipoprotein in group III were high, while level of high-density lipoprotein was weakened. Moreover, it was observed that administration of oxidized coconut oil albumin, blood urea nitrogen, and serum glucose as well as concentrations of serum electrolytes, such as calcium, magnesium, potassium, and sodium. This study also showed that group III mice had low levels of glutathione, deep-oxidized coconut oil has negative consequences and ought to be avoided.