Micro-Acoustic Holograms for Detachable Microfluidic Devices

Acoustic microfluidic devices have advantages for diagnostic applications, therapeutic solutions, and fundamental research due to their contactless operation, simple design, and biocompatibility. However, most acoustofluidic approaches are limited to forming simple and fixed acoustic patterns, or have limited resolution. In this study,a detachable microfluidic device is demonstrated employing miniature acoustic holograms to create reconfigurable, flexible, and high-resolution acoustic fields in microfluidic channels, where the introduction of a solid coupling layer makes these holograms easy to fabricate and integrate. The application of this method to generate flexible acoustic fields, including shapes, characters, and arbitrarily rotated patterns, within microfluidic channels, is demonstrated. This work presents a detachable microfluidic device employing acoustic holography, where acoustic holograms are utilized to produce flexible and reconfigurable acoustic fields within microfluidic channels. The device is characterized by its simplicity in fabrication and the introduction of a solid coupling layer, enhancing its versatility for integration with microfluidic systems to create reconfigurable, flexible, and high-resolution acoustic fields within microchannels.image