Association of pressure control rate and use of anti-hypertensive drugs among brazilian hypertensive patients

Objective: To analyze the association between the rate of blood pressure (BP) control and the use of antihypertensive drugs among hypertensive patients. Design and method: Analytical cross-sectional study, using data from the TeleMRPA platform, which records data from Residential Blood Pressure Measurements (MRPA). Variables used: age, sex, systolic BP (SBP) and diastolic BP (DBP) at office and residential, amount of medication in use, categorized into monotherapy, dual therapy, triple combination and four or more; BP variability. Comparison between categories was performed using the chi-square test and ANOVA test for comparison of means, considering a 95% confidence interval and significance level p<0.05. Results: Participants were 25,543 hypertensive patients, with a mean age of 60.6 (±14.4) years, minimum age 18 and maximum age 114 years. 63.1% were women and were older (mean 61.9 (±14.3) than men (58.5 (±14.2). The BP control rate was 42.3% in total sample, being proportionally higher among women (67.6%). The BP control rate was higher among young adults (<60 years) than among the elderly; 60 to 70 years. The amount of antihypertensive drugs was distributed in 42.6% in monotherapy, 37.4% double, 15.7% triple, and 4.4% four or more. Women used proportionally more triple combination (16.2%) than men (14.7%; p = 0.014) and in the other combinations there was no difference in the distribution of therapies and gender. than among the elderly (38.2%); drug combinations had higher proportions among the elderly. BP control rates were higher among those on monotherapy (42.7%) and dual combination (43.4%) than among the elderly what a triple combination (41.4%) and four or more (32.5%). Conclusions: The BP control rate was higher among women and among young adults. Monotherapy was more present among young adults and as the amount of drug combination increased, the rate of BP control decreased.