Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for High Altitude Medicine & Biology

High Altitude Medicine & BiologyVol. 24, No. 3 AnnouncementFree AccessRosalind Franklin Society Proudly Announces the 2022 Award Recipient for High Altitude Medicine & BiologyColleen G. JulianColleen G. JulianBiomedical Informatics, University of Colorado School of Medicine, Aurora, CO, USASearch for more papers by this authorPublished Online:12 Sep 2023https://doi.org/10.1089/ham.2023.29030.rfs2022AboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail The Rosalind Franklin Society (RFS), in partnership with Mary Ann Liebert, Inc., publishers, enthusiastically congratulate our distinguished recipient of the 2022 annualRFS Award in Sciencefor this journal, which recognizes the outstanding research and published work of women and underrepresented minority scientists, physicians, and engineers.William Mundo, Lilian Toledo-Jaldin, Alexandrea Heath-Freudenthal, Jaime Huayacho, Litzi Lazo-Vega, Alison Larrea-Alvarado, Valquiria Miranda-Garrido, Rodrigo Mizutani, Lorna G. Moore, Any Moreno-Aramayo, Richard Gomez, Patricio Gutierrez, and Colleen G. Julian, “Is Maternal Cardiovascular Performance Impaired in Altitude-Associated Fetal Growth Restriction?” High Altitude Medicine & Biology 23, no. 4 (December 2022): 352–360, http://doi.org/10.1089/ham.2022.0082.AbstractThe incidence of fetal growth restriction (FGR) is elevated in high altitude resident populations. This study aims to determine whether maternal central hemodynamics during the last trimester of pregnancy are altered in high altitude FGR. In this cross-sectional study of maternal-infant pairs, maternal heart rate, cardiac output (CO), stroke volume, and systemic vascular resistance (SVR) were assessed as were, uterine artery (UtA) resistance indices and fetal measures. Maternal venous soluble fms-like tyrosine kinase-1 (sFlt1) levels were measured. FGR pregnancies had reduced CO, elevated SVR and UtA resistance, fetal brain sparing, and increased maternal sFlt1 versus controls. Maternal SVR was positively associated with UtA resistance and inversely associated with middle cerebral artery resistance and birth weight. Maternal sFlt1 was greater in FGR than controls and positively associated with UtA pulsatility index. Women with elevated sFlt1 levels also tended to have lower CO and higher SVR.BiosketchColleen Julian is an associate professor in the department of biomedical informatics at the University of Colorado School of Medicine. She is a faculty member of the integrated physiology and human medical genetics and genomics graduate programs and the curriculum director for the National Institutes of Health (NIH)-sponsored Program to Increase Diversity among Individuals Engaged in Health-Related Research (PRIDE) academy at the University of Colorado. Her research focuses on human physiologic responses and genetic adaptations to hypoxia, particularly how these processes modify maternal vascular adaptation to pregnancy, fetal growth, and the long-term health of affected offspring. Her team takes advantage of natural variability between populations in the frequency of hypoxia-associated vascular disorders of pregnancy at high altitudes to identify biological pathways regulating fetal growth and hypertensive disorders of pregnancy.FiguresReferencesRelatedDetails Volume 24Issue 3Sep 2023 InformationCopyright 2023, Mary Ann Liebert, Inc., publishersTo cite this article:Colleen G. Julian.Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for High Altitude Medicine & Biology.High Altitude Medicine & Biology.Sep 2023.157-157.http://doi.org/10.1089/ham.2023.29030.rfs2022Published in Volume: 24 Issue 3: September 12, 2023PDF download