Pre- TAVI aortic annulus sizing: comparison between manual and semi- automated new generation software measurements in operators with different experience

Objectives: Aim of the study is to compare manual and semiautomatic measurements for aortic annulus assessment among different operators. Methods: Eighty patients who underwent TAVI were retrospectively enrolled. The measurements manually performed by an experienced reader for aortic annulus (minimum and maximum diameters, perimeter, area), annulus - to- coronary ostia distance and time needed for the whole evaluation, were collected. The same operator (observer 1) and two less experienced readers (observer 2 and 3, with >5 years and 1 year of experience, respectively) assessed the same measurements using a semiautomatic software. Differences between manual and semiautomatic measurements, reading time and suggested valves size derived by CT were compared. Results: Very good correlations were found between manual and software - aided measurements for aortic annulus area and perimeter in comparison with standard measurements for the three readers (ICC range 0.81-0.98). Good correlations were found for the distance with coronary ostia(0.75-0.79). The same areaderived prosthesis size for manual and semiautomatic measurements was selected in 96% of cases for observer 1; very good correlations were also found for observer 2 and 3 (ICC = 0.89 and 0.88, respectively). Using semiautomatic measurements, the mean time needed for CT images was significantly lower for observers 1 and 2 (1.50 and 1.72versus 3.14 min), respectively. Conclusions: Pre- TAVI CT using semiautomatic software allows accurate and reproducible measurements, reducing reconstruction time up to 50% and is reliable even for operators with different experience. Advances in knowledge: The use of semiautomatic dedicated software for CT in TAVI planning is reliable even for operators without long time experience and allows accurate and reproducible measurements improving pre- TAVI workflow.