Access to isoindole-derived BODIPYs by an aminopalladation cascade

Here, we present a new route to dyes of the BODIPY family. We first built up a N-Boc-protected dipyrromethene scaffold via an aminopalladation cascade. Subsequentially, the pyrrole moiety was deprotected and the BF2 unit inserted. Depending on the terminating reaction, BODIPYs with either aryl or alkynyl moieties were accessible. A fast access to isoindole BODIPYs by employing an aminopalladation cascade is presented. Depending on the termination mode either meso-aryl or meso-alkynyl BODIPYs are obtained.