Exploitation of bis(tert-butylaminomethyl)pyridine as a chemical modifier in a carbon paste electrode for sensitive and selective potentiometric determination of Al³⁺ ion in pharmaceutical and water samples

The fabrication of a novel bis(tert-butylaminomethyl)pyridine pincer ligand-based ionophore in a carbon paste electrode (CPE) matrix for Al3+ ions was investigated. With a Nernstian slope of 20.05 +/- 0.27 mV decade(-1) and a low detection limit of 1.0x10(-7) mol L-1, the electrode demonstrated an excellent response for the Al3+ ion over a broad concentration range from 1.0x10(-7) to 1.0x10(-1) mol L-1. The formula for the graphite paste that produced the greatest results was 69.44% graphite, 27.78% tricresyl phosphate (TCP) binder, and 2.78% ionophore. This pincer ligand-based electrode worked well with aqueous Al3+ solutions that had pH values between 2.5 and 5.5. It may be used for at least 4 months without any detectable potentials digression and has a reasonably quick response time (5 s). The suggested graphitic paste electrode demonstrated strong Al3+ ion selectivity over a broad range of other cations. The isothermal coefficient of the electrode, which was determined to be 0.2884x10(-3) V degrees C-1, was calculated by looking at the impact of test solution temperature on electrode potentials. The suggested electrode was also applied to non-aqueous media with an aqueous-non-aqueous volume ratio of up to 75:25. The data acquired using this CPE as an indicator electrode for the potentiometric measurement of Al3+ ions in several actual samples was equivalent to that attained using atomic absorption spectroscopy (AAS).