Economic Hardship and Associated Factors of Women With Early-Stage Breast Cancer Prior to Chemotherapy Initiation

This study explored economic hardship (EH) in 248 women who were prescribed chemotherapy for earlystage BC prior to or at their first chemotherapy treatment (baseline) and whether there are differences by race, area deprivation, stress, symptom distress, and social support. Black race, area of greater deprivation, higher perceived, and lower social support can predict higher EH. Screening for EH can identify at risk patients. Introduction: Economic hardship (EH) can negatively influence cancer outcomes. Little is known about the factors that are associated with higher levels of EH among patients with breast cancer (BC). This paper describes EH in women with early-stage BC prior to or at their first chemotherapy treatment (baseline) and explores whether there are differences by race, area deprivation, stress, symptom distress, and social support. Patients and Methods: A descriptive comparative/correlational design was employed using baseline data of a multisite, longitudinal, multimethod study comparing the symptom experience and management prior to prescribed chemotherapy for women with earlystage BC. Participants completed measures for EH, perceived stress, symptom distress, and social support. Race was measured by self-report. Area depr ivation indices (ADI) measur ing neighborhood economic factors were calculated from publicly available websites. Results: Participants (N = 248; age = 52.9 + 12.3 years) were 62% White and 38% Black, 54% partnered, and 98% insured. Compared to White patients, Black patients reported higher (worse) EH (1.2 + 3.0 vs. -0.7 + 2.4), lived in areas of greater deprivation (80.1 + 2.1 vs. 50.5 + 23.5),and were more likely to report inadequate household income (Black: 30.5%; White: 11.1%). Adjusting for race and age, being Black (P< .001), living in an area of greater deprivation (P = .049), higher perceived stress (P = .008), lower perceived appraisal (P = .040), and less tangible support (P < .001) contributed to greater EH. Worse symptom distress trended toward greater EH (P = .07). Conclusions: This study emphasizes the importance of incorporating baseline holistic assessment to identify patients most likely to exper ience EH dur ing ear ly-stage BC treatment.