Evaluation of Artifact Appearance and Burden in Pediatric Brain Tumor MR Imaging with Compressed Sensing in Comparison to Conventional Parallel Imaging Acceleration.

Clinical magnetic resonance imaging (MRI) aims for the highest possible image quality, while balancing the need for acceptable examination time, reasonable signal-to-noise ratio (SNR), and lowest artifact burden. With a recently introduced imaging acceleration technique, compressed sensing, the acquisition speed and image quality of pediatric brain tumor exams can be improved. However, little attention has been paid to its impact on method-related artifacts in pediatric brain MRI. This study assessed the overall artifact burden and artifact appearances in a standardized pediatric brain tumor MRI by comparing conventional parallel imaging acceleration with compressed sensing. This showed that compressed sensing resulted in fewer physiological artifacts in the FLAIR sequence, and a reduction in technical artifacts in the 3D T1 TFE sequences. Only a slight difference was noted in the T2 TSE sequence. A relatively new range of artifacts, which are likely technique-related, was noted in the 3D T1 TFE sequences. In conclusion, by equipping a basic pediatric brain tumor protocol for 3T MRI with compressed sensing, the overall burden of common artifacts can be reduced. However, attention should be paid to novel compressed-sensing-specific artifacts.