A Quantitative Study for Evaluating Risk Factors in Routine Perioperative Assessment During Elective Bariatric Surgery Regarding the Development of Postoperative Delirium

Abstract Background: Postoperative delirium (POD) is associated with long term physical and cognitive impairment. Identification of eligible biomarkers is desirable. In this subanalysis of data collected during the prospective observational CESARO study we investigate the relevance of preoperative organ dysfunctions on the onset of POD.Methods: N = 98 Patients undergoing laparoscopic bariatric surgery were screened for POD using the Nursing Delirium Screening Scale (Nu-DESC). All preoperative assessed routine data including laboratory results were investigated for association with the development of POD.Results: Twenty percent of patients had POD of short duration. Obstructive Sleep Apnea (OSAS) as well as elevated BUN and low HKT were identified as predictors.Conclusion: POD incidence was comparable to other studies nonetheless our patients had only marginal risk factors. Here identified parameters might be another piece to the answer of the question: which are correlating biomarkers to the pathophysiologic process of delirium onset?