Supplementary Tables 1-14 from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma

File contains supplementary tables and figures for the main article. Supplementary Table 1 - Source for tools and databases used in the methods for analysis. Supplementary Table 2 - Summary of Somatic Point and Indel Mutation across the three breeds. Supplementary Table 3 - Summary of GISTIC-defined recurrent large-scale SCNAs and gene frequency. Supplementary Table 4 - List of GISTIC classified amplification genes. See attached excel spreadsheet. Supplementary Table 5 - List of GISTIC classified deletion genes. See attached excel spreadsheet. Supplementary Table 6 - List of GISTIC genes and their predicted roles in cancer. Supplementary Table 7 - Significantly over-represented pathways for GISTIC- and MuSiC-defined genes. Supplementary Table 8 - Significantly mutated genes as identified by MuSiC and the proportion of samples per breed that show mutation in them. Supplementary Table 9 - Putative driver genes as detected by MutSigCV algorithm Supplementary Table 10 - Putative driver genes assessed by VEP high-impact mutations and their variant allele frequency. Supplementary Table 11 - Mutations and their effects on p53 protein. Supplementary Table 12 - Mutations and their effects on SETD2 protein. Supplementary Table 13 - Count of non-silent mutations per breed/per germline for OSA susceptibility genes Supplementary Table 14 - Overlap of GISTIC-defined recurrent SCNA genes between humans and dogs. See attached excel spreadsheet.