Prospective evaluation of the tolerability and efficacy of niraparib dosing based on baseline body weight and platelet count: Results from the PRIMA/ENGOT-OV26/GOG-3012 trial.
Cancer(2023)
摘要
In PRIMA, similar dose intensity, similar efficacy, and improved safety were observed with the ISD compared with the FSD regimen.
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关键词
individualized starting dose,niraparib,ovarian cancer,poly(ADP-ribose) polymerase inhibitors/adverse effects,poly(ADP-ribose) polymerase inhibitors/therapeutic use
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