Covid-19 in Brazil: A Cross-Sectional Immuno-Epidemical and Genomic Evaluation in a Pre-Omicron Era

The seventh human coronavirus, was discovered and reported primarily in Wuhan, China. After intense seasons with repercussions in all areas ofhumanity, the pandemic demonstrates a new perspective. In Brazil, the pandemic concept has had impacts in vast areas, including mainly hospitals. This present study aims to describe, present and synthesize data that correlate the symptoms of passive and/or active patients for Covid-19 and their respective results of igg/igm serological tests in hospitals in cruzeiro, São Paulo. The form had been applied to 333 people and obtained conclusive results and several symptoms presented, in addition, asymptomatic cases were also analyzed and directed in the genomic study of variants of concern, as well as vaccination data in the study region. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement This study was funded by the Municipality of Cruzeiro, Sao Paulo, Brazil. ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: This work was approved by Ethic Comitee of federal University of Sao Paulo, Campus Diadema, Sao Paulo, Brazil. I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable. Yes All data produced in the present study are available upon reasonable request to the authors. All data produced in the present work are contained in the manuscript.