Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity.

Brigitte I Frohnert,Mohamed Ghalwash,Ying Li,Kenney Ng,Jessica L Dunne,Markus Lundgren,William Hagopian,Olivia Lou,Christiane Winkler,Jorma Toppari,Riitta Veijola,Vibha Anand

Diabetes care（2023）

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摘要

The 15-year risk of progression to type 1 diabetes risk varies markedly from 18 to 88% based on the stringency of mIA definition. While initial categorization identifies highest-risk individuals, short-term follow-up over 2 years may help stratify evolving risk, especially for those with less stringent definitions of mIA.

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关键词

multiple islet autoimmunity,diabetes,ontology-driven

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