A step-by-step approach for assessing acute oral toxicity without animal testing for additives of quasi-drugs and cosmetic ingredients

Hajime Kojima,Tokio Nakada,Akiko Yagami,Hiroaki Todo,Jihei Nishimura,Mio Yagi,Keiko Yamamoto,Mariko Sugiyama,Yoshiaki Ikarashi,Hitoshi Sakaguchi,Masahiko Yamaguchi, Morihiko Hirota, Sakiko Aizawa, Shota Nakagawa, Shigenobu Hagino,Masato Hatao

Current Research in Toxicology（2023）

引用 1|浏览5

暂无评分

摘要

•The step-by-step approach challenged in a weight of evidence assessment of acute oral toxicity.•A combination of safety data for acute oral toxicity, including a neutral red uptake cytotoxicity assay using BALB/c3T3 cells (3T3-NRU cytotoxicity assay).•Available to assess the acute oral toxicity of quasi-drugs or cosmetic ingredients.

查看译文

关键词

Acute oral toxicity,3T3-NRU cytotoxicity assay,Non-animal,NICEATM,EURL ECVAM,OECD

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要