A Comprehensive Study on the Timing Limits of the TOFPET2 ASIC and on Approaches for Improvements
IEEE Transactions on Radiation and Plasma Medical Sciences(2022)
摘要
Novel electronic readout schemes of analog silicon photomultipliers (SiPMs) have shown impressive timing performance of
$\gamma $
-detectors in positron emission tomography (PET). However, transferring these novel concepts to the system level is a key to exploit the improved coincidence time resolution (CTR) in (pre-)clinical imaging. In this study, the commercially available TOFPET2 application-specific integrated circuits (ASICs) from PETsys Electronics S.A. is tested in terms of the best achievable CTR. The measurable CTR limits will be obtained by state-of-the-art high-frequency (HF) readout, minimizing the impact of the electronic front end on the time resolution. We achieved (73 ± 1) ps with the HF readout and (134 ± 10) ps with the TOFPET2 ASIC for a Ce-, and Ca-doped lutetium-oxyorthosilcate (LYSO) crystal of 2
$\times $
2
$\times $
3 mm2 size. We show that SiPM signal amplification and an effectively reduced TOFPET2 input stage impedance boost the CTR of a 20-mm high LYSO:Ce crystal to 187 ± 8 ps. Our studies also lead to the observation of side peaks in the coincidence time difference spectrum. These peaks are studied in depth and a conclusion on the ASIC for 100-ps PET applications is drawn.
更多查看译文
关键词
Coincidence time resolution (CTR),front-end electronics,positron emission tomography (PET),radiation detectors for medical applications,timing detectors,time-of-flight positron emission tomography (TOF-PET2) application-specific integrated circuits (ASIC)
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要