Pharmacokinetics and bioequivalence of two methylprednisolone tablet formulations in healthy Chinese subjects under fasting and fed conditions.

Lianlian Fan,Peiwen Zhang,Chunyan Gan,Qian Huang, Zhen Shen,Xue Xiao, Ying Yang,Daicong Qiu,Gang Mai,Jianzhong Shentu

International journal of clinical pharmacology and therapeutics（2023）

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摘要

The test methylprednisolone 16 mg tablet produced in China is bioequivalent to the reference formulation (Medrol) in healthy Chinese subjects measured under both fasting and fed conditions. Both formulations were well tolerated by all study participants.

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关键词

methylprednisolone, pharmacokinetics, bioequivalence, safety

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