Adequate vitamin B 12 and folate status of Norwegian vegans and vegetarians.
The British journal of nutrition(2022)
摘要
Plant-based diets may increase the risk of vitamin B deficiency due to limited intake of animal-source foods, while dietary folate increases when adhering to plant-based diets. In this cross-sectional study, we evaluated the B and folate status of Norwegian vegans and vegetarians using dietary B intake, B and folic acid supplement use, and biomarkers (serum B (B), plasma total homocysteine (tHcy), plasma methylmalonic acid (MMA) and serum folate). Vegans ( 115) and vegetarians ( 90) completed a 24-h dietary recall and a FFQ and provided a non-fasting blood sample. cB, a combined indicator for evaluation of B status, was calculated. B status was adequate in both vegans and vegetarians according to the cB indicator; however 4 % had elevated B. Serum B, tHcy, MMA concentrations and the cB indicator (overall median: 357 pmol/l, 9·0 µmol/l, 0·18 µmol/l, 1·30 (cB)) did not differ between vegans and vegetarians, unlike for folate (vegans: 25·8 nmol/l, vegetarians: 21·6 nmol/l, = 0·027). Serum B concentration < 221 pmol/l was found in 14 % of all participants. Vegetarians revealed the highest proportion of participants below the recommended daily intake of 2 µg/d including supplements (40 . 18 %, < 0·001). Predictors of higher serum B concentrations were average daily supplement use and older age. Folate deficiency (< 10 nmol/l) was uncommon overall (< 2·5 %). The combined indicator cB suggested that none of the participants was B-depleted; however, low serum B concentration was found in 14 % of the participants. Folate concentrations were adequate, indicating adequate folate intake in Norwegian vegans and vegetarians.
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关键词
B12 dietary intake,Folate,Homocysteine,Methylmalonic acid,Vegans,Vegetarians,Vitamin B12
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