Vitamin D supplementation positively affects anthropometric indices: Evidence obtained from an umbrella meta-analysis.

Despite the growing evidence from meta-analyses on vitamin D's anti-obesity properties, their results are controversial. The current umbrella review was performed to assess the available evidence and provide a conclusive explanation in this regard. The international databases PubMed, Scopus, Embase, Web of Science and Google Scholar were systematically searched till March, 2022. A random-effects model was used to run the meta-analysis. All meta-analyses that examined the effect of vitamin D supplementation on BW, BMI, WC, and fat mass were included. Findings of 14 meta-analyses revealed that vitamin D supplementation reduced body mass index (BMI) (ES: -0.11 kg/m; 95% CI: -0.18, -0.05, ?0.001; = 61.0%, < 0.001), and waist circumference (WC) (ES = -0.79 cm; 95% CI: -1.20, -0.37; < 0.001; = 46.5%, = 0.096) in comparison to control group. However, the effects of vitamin D on body weight (ES = -0.16 kg, 95% CI: -0.36, 0.04; = 0.125; = 57.0%, = 0.017), and fat mass (ES: 0.02, 95% CI: -0.20, 0.24, = 0.868; = 0.0%, = 0.531) were not considerable. Vitamin D supplementation significantly improved levels of obesity indices such as BMI, and WC.