Investigation on the activity distribution of positron products in PMMA target irradiated by carbon ion beam

Abstract In the heavy ion radiotherapy, the dose distribution is an important index to ensure the therapeutic effect. But it can not be directly measured during a treatment. Positron-emitting radionuclides (10 C, 11 C, and 15 O et al.) produced in the treatment process are deposited along the path and the end of the beam trajectory, so the positron activity distribution can be used to monitor the dose distribution of carbon ions. In this paper, we present results of measurements of positron activity distributions with a developed scanner system. Then the relationship between the activity distribution of positrons and the dose distribution of carbon ions is studied. The research shows that the activity distribution of positrons is quite similar to that of carbon ions in the direction of penetration depth. The activity peak position of positrons is smaller than the dose peak position of carbon ions, and this difference increases along with the increase of carbon ion beam energy. These experimental results are consistent with the GATE simulation results. It is found that the detector system can distinguish shift of peak position of 3 mm that corresponds change of a particle energy of 4 MeV/u. This indicates that the positron scanner system had been successfully developed for heavy ion therapy equipment.