Accelerated 3D T2-weighted images using compressed sensing for pediatric brain imaging

Purpose The purpose of this study was to compare the image quality of the 3D T2-weighted images accelerated using conventional method (CAI-SPACE) with the images accelerated using compressed sensing (CS-SPACE) in pediatric brain imaging. Methods A total of 116 brain MRI (53 with CAI-SPACE and 63 with CS-SPACE) were obtained from children 16 years old or younger. Quantitative image quality was evaluated using the apparent signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). The sequences were qualitatively evaluated for overall image quality, general artifact, cerebrospinal fluid (CSF)-related artifact, and grey-white matter differentiation. The two sequences were compared for the total and two age groups (< 24 months vs. ≥ 24 months). Results Compressed sensing application in 3D T2-weighted imaging resulted in 8.5% reduction in scanning time. Quantitative image quality analysis showed higher apparent SNR (median [Interquartile range]; 29 [25] vs. 23 [14], P = 0.005) and CNR (0.231 [0.121] vs. 0.165 [0.120], P = 0.027) with CS-SPACE compared to CAI-SPACE. Qualitative image quality analysis showed better image quality with CS-SPACE for general ( P = 0.024) and CSF-related artifact ( P < 0.001). CSF-related artifacts reduction was prominent in the older age group (≥ 24 months). Overall image quality ( P = 0.162) and grey-white matter differentiation ( P = 0.397) were comparable between CAI-SPACE and CS-SPACE. Conclusion Compressed sensing application in 3D T2-weighted images modestly reduced acquisition time and lowered CSF-related artifact compared to conventional images of the pediatric brain.