Antioxidant System and Ions Concentrations After Femoral Neck and Resurfacing Hip Arthroplasty

Background: Oxidative stress is a disruption of the pro-oxidative-antioxidant balance, caused by excessive production or in-effective removal of reactive oxygen species. Material/Methods: The study included 42 male patients aged 38 to 69 years. The first group consisted of 21 men with osteoar-thritis after primary hip arthroplasty using the Smith & Nephew Birmingham Hip Resurfacing implant. The sec-ond group included 21 men after hip arthroplasty using the femoral neck SPIRON K-implant. In both groups, concentrations of ions, the antioxidant system in the blood, and parameters of oxidative stress were evaluat-ed twice. Clinical assessment using the Western Ontario and McMaster Universities Osteoarthritis Index, Harris Hip Score, and Short Form (12) Health Survey (SF-12) scales was performed. Results: Concentrations of metal ions in the blood and the level of oxidative stress were significantly higher in the re-surfacing group than in the femoral neck arthroplasty group. The response of the antioxidant system was sig-nificantly greater in the femoral neck arthroplasty group. During clinical evaluation, groups did not show sig-nificant differences, with the exception of greater shortening of the operated limb and a lower score in the mental-sphere of the SF-12 scale in the resurfacing arthroplasty group. Conclusions: Resurfacing hip arthroplasty increased oxidative stress, increased the concentration of metal ions, and did not affect alignment of the abbreviation of the operated limb. A significant improvement in the quality of life of patients in the mental sphere according to the SF-12 occurred after the application of resurfacing arthroplas-ty, in the first month after the procedure.