D-37 | Racial Disparities in the Utilization and Outcomes of Percutaneous Left Atrial Appendage Occlusion in the United States

BackgroundWe aimed to ascertain the racial differences in utilization and outcomes of patients undergoing left atrial appendage occlusion (LAAO) procedure.MethodsWe utilized the Nationwide Inpatient Sample (NIS) from 2017–18. Primary outcome was in-hospital mortality. Secondary outcomes were stroke, acute kidney injury (AKI) requiring dialysis, vascular complications, pooled cardiovascular events (CVE) (including myocardial infarction, shock, cardiac arrest, cardiac tamponade requiring pericardiocentesis and hemopericardium), major bleeding, pulmonary complications, length of stay (LOS) and hospitalization charges. Multivariate logistic regression was used to adjust for baseline characteristics.Results29,135 hospitalizations underwent LAAO device implantation, of which 25,638 (88%) were Whites, 13,110 (4.5%) were Blacks and 18,937 (6.5%) were Hispanics. There was no difference in the in-hospital mortality between the three ethnicities (Figure 1), however, AKI requiring dialysis was significantly higher in Blacks. There was no difference in the rates of other procedural outcomes (stroke, vascular complications, CVE, major bleeding, pulmonary complications) between the three ethnicities. On a multivariable analysis, Blacks had increased odds of AKI requiring dialysis (OR:6.06, CI:2.05-17.07; p<0.01), and Hispanics had longer LOS (0.57 days longer, p=0.02) and hospitalization charges ($40,464 higher, p<0.01).ConclusionsDisclosuresU. Baber: Amgen and AstraZeneca: Honoraria; S. Agarwal Nothing to disclose. A. Bansal Nothing to disclose. M. Khattab Nothing to disclose. S. Krishan Nothing to disclose. K. H. Akhtar Nothing to disclose. A. H. Jafry Nothing to disclose. N. Garg Nothing to disclose. M. F. Anwaar Nothing to disclose. S. Saju Nothing to disclose. C. Fleming Nothing to disclose. BackgroundWe aimed to ascertain the racial differences in utilization and outcomes of patients undergoing left atrial appendage occlusion (LAAO) procedure. We aimed to ascertain the racial differences in utilization and outcomes of patients undergoing left atrial appendage occlusion (LAAO) procedure. MethodsWe utilized the Nationwide Inpatient Sample (NIS) from 2017–18. Primary outcome was in-hospital mortality. Secondary outcomes were stroke, acute kidney injury (AKI) requiring dialysis, vascular complications, pooled cardiovascular events (CVE) (including myocardial infarction, shock, cardiac arrest, cardiac tamponade requiring pericardiocentesis and hemopericardium), major bleeding, pulmonary complications, length of stay (LOS) and hospitalization charges. Multivariate logistic regression was used to adjust for baseline characteristics. We utilized the Nationwide Inpatient Sample (NIS) from 2017–18. Primary outcome was in-hospital mortality. Secondary outcomes were stroke, acute kidney injury (AKI) requiring dialysis, vascular complications, pooled cardiovascular events (CVE) (including myocardial infarction, shock, cardiac arrest, cardiac tamponade requiring pericardiocentesis and hemopericardium), major bleeding, pulmonary complications, length of stay (LOS) and hospitalization charges. Multivariate logistic regression was used to adjust for baseline characteristics. Results29,135 hospitalizations underwent LAAO device implantation, of which 25,638 (88%) were Whites, 13,110 (4.5%) were Blacks and 18,937 (6.5%) were Hispanics. There was no difference in the in-hospital mortality between the three ethnicities (Figure 1), however, AKI requiring dialysis was significantly higher in Blacks. There was no difference in the rates of other procedural outcomes (stroke, vascular complications, CVE, major bleeding, pulmonary complications) between the three ethnicities. On a multivariable analysis, Blacks had increased odds of AKI requiring dialysis (OR:6.06, CI:2.05-17.07; p<0.01), and Hispanics had longer LOS (0.57 days longer, p=0.02) and hospitalization charges ($40,464 higher, p<0.01). 29,135 hospitalizations underwent LAAO device implantation, of which 25,638 (88%) were Whites, 13,110 (4.5%) were Blacks and 18,937 (6.5%) were Hispanics. There was no difference in the in-hospital mortality between the three ethnicities (Figure 1), however, AKI requiring dialysis was significantly higher in Blacks. There was no difference in the rates of other procedural outcomes (stroke, vascular complications, CVE, major bleeding, pulmonary complications) between the three ethnicities. On a multivariable analysis, Blacks had increased odds of AKI requiring dialysis (OR:6.06, CI:2.05-17.07; p<0.01), and Hispanics had longer LOS (0.57 days longer, p=0.02) and hospitalization charges ($40,464 higher, p<0.01). Conclusions DisclosuresU. Baber: Amgen and AstraZeneca: Honoraria; S. Agarwal Nothing to disclose. A. Bansal Nothing to disclose. M. Khattab Nothing to disclose. S. Krishan Nothing to disclose. K. H. Akhtar Nothing to disclose. A. H. Jafry Nothing to disclose. N. Garg Nothing to disclose. M. F. Anwaar Nothing to disclose. S. Saju Nothing to disclose. C. Fleming Nothing to disclose. U. Baber: Amgen and AstraZeneca: Honoraria; S. Agarwal Nothing to disclose. A. Bansal Nothing to disclose. M. Khattab Nothing to disclose. S. Krishan Nothing to disclose. K. H. Akhtar Nothing to disclose. A. H. Jafry Nothing to disclose. N. Garg Nothing to disclose. M. F. Anwaar Nothing to disclose. S. Saju Nothing to disclose. C. Fleming Nothing to disclose.