Efficient Bayesian Computation for Low-Photon Imaging Problems*

This paper studies a new and highly efficient Markov chain Monte Carlo (MCMC) methodology to perform Bayesian inference in low-photon imaging problems, with particular attention given to situations involving observation noise processes that deviate significantly from Gaussian noise, such as binomial, geometric, and low-intensity Poisson noise. These problems are challenging for many reasons. From an inferential viewpoint, low-photon numbers lead to severe identifiability issues, poor stability, and high uncertainty about the solution. Moreover, low-photon models often exhibit poor regularity properties that make efficient Bayesian computation difficult, e.g., hard nonnegativity constraints, nonsmooth priors, and log-likelihood terms with exploding gradients. More precisely, the lack of suitable regularity properties hinders the use of state-of-the-art Monte Carlo methods based on numerical approximations of the Langevin stochastic differential equation (SDE), as both the SDE and its numerical approximations behave poorly. We address this difficulty by proposing an MCMC methodology based on a reflected and regularized Langevin SDE, which is shown to be well-p osed and exponentially ergodic under mild and easily verifiable conditions. This then allows us to derive four reflected proximal Langevin MCMC algorithms to perform Bayesian computation in low-photon imaging problems. The proposed approach is demonstrated with a range of experi-ments related to image deblurring, denoising, and inpainting under binomial, geometric, and Poisson noise.