Profile of type B natriuretic peptides in diabetic patients in Brazzaville

Fylla Onanga Koumou,Raissa Mayanda, Yvon Mbouamboua,Monde Ikia,Barnes Yoyo, Rod Ibara, Jeanne Gambomi Kiba, Aliocha Nkodila Natuhoyila,Etienne Mokondjimobé, Henri Germain Monabeka, Martin Diatewa, Benjamin Longo-Mbenza

The Journal of Medical Research(2021)

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摘要
Background and Objective: Cardiovascular disease is the leading cause of morbidity and mortality in diabetic patients. The objective of this study was to determine the frequency of diabetic patients with a serum BNP level greater than 100 pg / ml and to establish the relationship between BNP and other variables. Methods: This is a cross-sectional study carried out in 50 diabetic patients admitted to the metabolic diseases department of the University Hospital of Brazzaville between May and October 2018. Results: A single type 2 diabetic patient presented a BNP = 187.4 pg / ml, a frequency of 2%. BNP level was associated with age (p = 0.005) and creatinine (p = 0.003). The small number of samples and an untargeted population did not allow us to profile BNP in diabetic patients. Conclusion: the mean BNP is high in diabetics in Congo Brazzaville despite a small sample size which does not allow the results to be generalized.
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