Togni-Ⅱ Reagent Mediated Selective Hydrotrifluoromethylation and Hydrothiolation of Alkenes

Based on the redox reactions of Togni-Ⅱ reagent and thiols,a thiol-tuned selective functionalization of unactivated olefins was dis-closed.In combination with aryl thiols,stoichiometric amount of Togni-Ⅱ reagent prompted a hydrotrifluoromethylation of alkenes,in which,aryl thiols played as reductant and hydrogen source;while by utilization of alkyl thiols,catalytic amount of Togni-Ⅱ reagent ini-tiated thiol-ene and thiol-yne reactions.The reported applications are characterized by their operational simplicity and wide func-tional group tolerance.