Study of the relation between arterial oxygen saturation and intradialytic hypertension in regular hemodialysis patients

Background Patients with IDHTN have an increased risk for hospitalizations and mortality. The pathogenesis of IDHTN is not well understood. Hypoxemia is thought to stimulate the blood pressure (BP) elevation. The aim of this work was to study the changes of the arterial oxygen saturation (SaO2) during hemodialysis (HD) and their relations to intradialytic hypertension (IDHTN). Patients and methods This is a prospective observational study that analyzed SaO2 and BP changes during HD sessions in 75 regular HD patients over 6 months. Patients were divided into two groups: group A included patients without intradialytic hypertension (non-IDHTN) and group B included patients with persistent IDHTN group. Results Group B patients had significantly lower predialysis, intradialytic, and postdialysis SaO2 levels compared with group A (P Conclusion Decreased SaO2 before and during HD sessions may be involved in the induction of IDHTN.