Triply Periodic Minimal Surface-Based Porous Scaffold Design and Analysis Subjected to Hard Tissue Reconstruction

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摘要
Porous structures based on triply periodic minimal surfaces (TPMS) have occurred as appropriate candidates for scaffold design with high level of porosity and promising strength for bone replacement. This work describes a suitable procedure for design and modeling of 3D architecture of TPMS-based gyroid and primitive structures and identifying the optimal architecture for scaffold designing. Different models with varying porosity were reconstructed and analyzed to access the effective elastic moduli and compressive strength of each model. An optimal model that can be utilized in bone tissue replacement is identified eventually. Ti6Al4V which is considered as the best material for producing implants in conjunction with biocompatibility and strength is used in the study. The compression test performed by FEM revealed that the scaffold models with porosity level of 65 and 60% are best suited for cortical bone replacement and the model with 90% porosity can be used on the anatomical location, which are more inclined to cancellous bones.
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关键词
Tissue engineering, Porous scaffolds, TPMS, Gyroid, Primitive, Finite element analysis
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