P601 Takayasu arteritis in pediatrics

Introduction Takayasu arteritis is an idiopathic chronic granulomatous panarteritis predominantly affecting the aorta and its main branches. The diagnosis is based on a set of clinical, biological and radiological criteria. Observation Thes are two girls, averag age 12 years. They presented a decrease in visual acuity and high blood pressure. One of the two girls had right radial and brachial pulse abolished. In the two cases a bilateral edema was objectified. An hypokalemia was noted in one case. The angio scanner showed a stenosis of the right subclavian artery with stenosis of the aortic arch extended to both renal arteries, with complete occlusion of the right right renel artery. For the other child, the aortic angiocan showed non-stenosing focal thikening of the descendeng aorta, with pre stenosis occlusive from the origin of the right renel artery. There was no brain damage in the two cases. One of the two girls was treated with a high-dose corticosteroid with methotrexate and an antihypertensive drug. The other child was treated with potassium supplementation in addition to antihypertensive treatment. Conclusion Takayasu arteritis is a chronic vasculitis of unknown etiology. Rare in children, it is a worldwide disease with significant morbidity and mortality.