Proteomic profiling reveals a distinctive molecular signature for critically ill COVID-19 patients compared with asthma and chronic obstructive pulmonary disease

Zili Zhang,Fanjie Lin,Fei Liu,Qiongqiong Li,Yuanyuan Li,Zhanbei Zhu,Hua Guo,Lidong Liu,Xiaoqing Liu,Wei Liu,Yaowei Fang,Xinguang Wei,Wenju Lu

International Journal of Infectious Diseases（2022）

引用 11|浏览6

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摘要

•Formation of mucus plugs has been observed in critically ill COVID-19 patients.•Proteomic analyses of airway mucus were obtained by bronchoscopy or induced sputum.•Eight proteins specifically present in COVID-19 were found compared with chronic obstructive pulmonary disease and asthma.

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关键词

Critically ill COVID-19,Proteomic sequencing,Airway mucus,COPD,Asthma

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