Objective:
Using a musculoskeletal modelling framework, we aimed to (1) estimate knee joint loading using static optimization (SO); (2) explore different calibration functions in electromyogram (EMG)-informed models used in estimating knee load; and (3) determine, when using an EMG-informed stochastic method, if the measured joint loadings are solutions to the muscle redundancy problem when investigating only the uncertainty in muscle forces.
Methods
: Musculoskeletal models for three individuals with instrumented knee replacements were generated. Muscle forces were calculated using SO, EMG-informed, and EMG-informed stochastic methods. Measured knee joint loads from the prostheses were compared to the SO and EMG-informed solutions. Root mean square error (RMSE) in joint load estimation was calculated, and the muscle force ranges were compared.
Results
: The RMSE ranged between 192-674 N, 152-487 N, and 7-108 N for the SO, the calibrated EMG-informed solution, and the best fit stochastic result, respectively. The stochastic method produced solution spaces encompassing the measured joint loading up to 98% of stance.
Conclusion:
Uncertainty in muscle forces can account for total knee loading and it is recommended that, where possible, EMG measurements should be included to estimate knee joint loading.
Significance:
This work shows that the inclusion of EMG-informed modelling allows for better estimation of knee joint loading when compared to SO.
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关键词
Biomechanical Phenomena,Electromyography,Gait,Humans,Knee Joint,Models, Biological,Muscle, Skeletal,Prostheses and Implants,Walking
