Bioremidation of Spirulina Plantesis Against Deltamethrin Mediated Toxicity and Its Chemical Residues in Chicken Meat

Deltamethrin (DM) is a synthetic pyrethroid insecticide commonly used in veterinary and agriculture. However, both animal and human exposure is associated with hepatorenal toxicity. Our experimental goal was to assess the protective effects of Spirulina plantesis (SP) against DM-induced hepato-renal injury, growth performance, meat chemical composition and its residues in meat, liver and skin of broiler chickens. Sixty one-day-old Cobb broiler chicks were assigned to 4 experimental groups, each was divided into 3 replicates with five chicks each; 1st group received basal diet alone (Control), 2nd group supplemented with SP 20 g/kg diet, 3rd group supplemented with DM 300 mg/kg diet, and 4th group supplemented with DM and SP diet. All groups were received the treatment for 35 days. DM, decreased body weight, weight gain, and increased feed conversion rate. DM showed significant increase in ALT, AST, urea, creatinine and MDA and significant decrease in SOD, and GSH levels. Also, significant decrease in DM levels in meat, skin, and liver by SP with a reduction % 63.01, 63.00 and 62.90 % in meat, skin and liver, respectively. The DM intoxicated group showed significant decrease in protein and significant increase in fat, cholesterol and triglycerides when compared to control group. Histopathological changes were also recorded. Dietary SP improved these parameters parameters. Dietary inclusion of SP can be recommended due to the protective effects on DM induced toxicity in broiler chickens.