Parathyroidectomy is a reliable treatment option for chronic kidney disease patients with secondary hyperthyroidism (SHPT)

Background: Secondary hyperthyroidism (SHPT) is a common complication in chronic kidney disease patients undergoing peritoneal dialysis. It develops as a result of distortions in the regulation of calcium, phosphorus and parathyroid hormone (PTH). SHPT increases with decreasing kidney function. Factors that affect the levels of calcium, phosphorus, and PTH include diet, residual renal function, peritoneal transport properties, and dialysate calcium concentration. Treatment options for SHPT include pharmaceutical and surgical removal of parathyroid glands. Although there are treatment options for kidney disease patients with SHPT, little improvement has been made in the overall outcome of the patients. Method: Here, we present that parathyroidectomy is a treatment option for patients with SHPT. A test group (peritoneal dialysis patients with SHPT who had surgery plus forearm transplantation) were compared with control group (normal peritoneal dialysis patients without surgery). In both groups, clinical, biochemical and haematological profile assessments were done. Results: The test group after surgery show improved clinical, biochemical and haematological profile comparing with the control (non-surgery) group. Conclusion: parathyroidectomy (PTX) is a reliable treatment option for patients with SHPT, which brings about improvement in the biochemical, haematological, physiological and clinical parameters as compared with peritoneal dialysis patients with secondary hyperthyroidism without parathyroidectomy plus forearm transplantation.