COVID Feel Good – A Self-Help Virtual Therapeutic Experience for Overcoming the Psychological Distress of the COVID-19 Pandemic: Results from a European Multicentric Trial

The primary aim of the present study was to investigate the efficacy of a self-help virtual therapeutic experience (COVID Feel Good) for reducing the psychological burden experienced during the COVID-19 lockdown across different countries. For this purpose, we focused on participants recruited from June 2020 to May 2021 in the context of a European multicenter project including four university/academic sites. Primary outcome measures were depression, anxiety and stress symptoms, perceived stress levels and hopelessness. Secondary outcomes were the experienced social connectedness and the level of fear experienced during the COVID-19 pandemic. To assess the efficacy of the intervention in a multicentric context, we evaluated the strength of evidence supporting the COVID Feel Good computing a single summary estimate of the effect across the different countries. Using separate linear mixed-effect models, the most consistent result across the different countries was an improvement of the perceived stress level after the participation in the COVID Feel Good intervention. By pooling the results of the models using a random-effect meta-analysis, we found that COVID Feel Good intervention was associated a decrease in the perceived general distress [mean standardized effect size for general distress in the treatment groups compared to the control conditions was 0.52 (p = 0.007, 95% CI: 0.14, 0.89] and with an increase the perceived social connection [mean standardized effect size for social connection using COVID Feel Good compared to the control conditions was -0.50 (p = < 0.001, 95% CI: -0.76, -0.25)]. Globally findings suggest the efficacy of the proposed protocol and contribute the growing literature supporting the use of digital psychological interventions to reduce the psychological stress among general population during the COVID-19 crisis.