Quality consistency evaluation of commercial Impatiens Caulis by integrating UPLC-QTOF-MS/MS chemical profiling and UPLC-DAD multi-components quantification approaches

Ting Zeng,Shan-Shan Zhou,Jin-Di Xu, Xing-Yu Lin,He Zhu,Song-Lin Li,Ming Kong

Journal of Pharmaceutical and Biomedical Analysis（2022）

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摘要

•UPLC-QTOF-MS/MS based chemical profiling was firstly developed for qualitatively characterizing the Impatiens Caulis sample.•A sensitive UPLC-DAD method was firstly developed to quantify eleven compounds in the Impatiens Caulis sample.•The developed method was integrated to compare the quality consistency of commercial Impatiens Caulis samples.

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关键词

Impatiens Caulis,Quality consistency evaluation,UPLC-QTOF-MS/MS,UPLC-DAD

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