The Discussion On The Prognostic Factors Of Patients With Intrahepatic Massforming Cholangiocarcinoma And The Relationship With The Imaging Features Of Arterial Blood Supply Of Tumor

ACTA MEDICA MEDITERRANEA(2021)

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摘要
Objective: To discuss the prognostic factors of patients with Intrahepatic massforming cholangiocarcinoma and the relationship with the imaging features of arterial blood supply of tumor.Methods: From January 2010 to June 2020, a total of 184 Intrahepatic massforming cholangio-carcinoma patients admitted to our hospital treated with enhanced CT scan or MRI were included in this study. The clinical data were collected for a retrospective analysis, and they were grouped based on tumor blood supply status in the arterial phase of enhanced CT scan or MRI. Clinical features and prognostic indicators were analyzed. A regression model was performed to evaluate factors affecting the prognosis of patients with Intrahepatic massforming cholangiocarcinoma.Results: Through the comparison of lymphadenectasis, the largest diameter of the primary lesion, the level of CA19-9, the treatment program, and the abnormalities of perfusion enhancement in the combined arterial phase between two groups, the differences were statistically significant (P<0.05); the 1-year overall survival rate, 3-year overall survival rate and 5-year overall survival rate of rich blood supply group were significantly higher than those of the poor blood supply group (P<0.05); univariate analysis results showed that CA19-9>200U/ml, combined lymphadenectasis, the abnormalities of perfusion enhancement in the combined arterial phase, insufficient arterial blood supply were related to the prognosis of patients with Intrahepatic massforming cholangiocarcinoma (P<0.05); multivariate analysis results showed that combined lymphadenectasis and insufficient arterial blood supply were independent factors affecting the prognosis of patients with Intrahepatic massforming cholangiocar-cinoma (P<0.05).Conclusion: The prognosis of patients with Intrahepatic massforming cholangiocarcinoma is related to the presence of combined lymphadenectasis and the blood supply status in arterial phase; imaging features of arterial blood supply of tumor can be used to predict the prognosis of patients with Intrahepatic massforming cholangiocarcinoma.
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关键词
Intrahepatic massforming cholangiocarcinoma, prognosis, influencing factors, imaging, blood supply
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