Late Breaking Abstract - Clinical Variation In Presenting Characteristics Of Covid-19 At St George'S Hospital, London

Introduction: COVID-19 arrived as a new disease entity to the UK in early 2020. As one of the tertiary hospitals to admit COVID-19 patients, we collected data in order to characterise patients Method: Data was collected on 771 patients admitted with confirmed COVID-19 during the first 3 months of the pandemic, who had already been discharged or died. Presenting symptoms, co-morbidities, frailty, observations, ethnicity and mortality were noted. Results: The median age was 72 with a median clinical frailty score (CFS) and Charlson co-morbidity index (CCI) of 4. The most frequently reported symptoms were fever(62%), cough(60%) and breathlessness (57%) but older patients had more presentations with falls (34%) and confusion (37%). Older patients presented earlier compared with younger patients (2 vs 7 days). Patients with a CCI of 0 had a median age of 38 and frailty score of 2, whilst patients with CCI ≥5 had a median age of 82 and frailty score of 6. The most common co-morbidities were hypertension(42%), diabetes mellitus (31%)and chronic respiratory disease(16%). Data on ethnicity and mortality is undergoing further analysis Conclusion: This is a large single site cohort of COVID-19 patients. Older patients presented sooner after symptom onset. They were more likely to present with falls and confusion and have a higher frailty score and co-morbidity index. Further multivariate analysis is ongoing to examine additional variables.