Effects of a Lifestyle Change Intervention on Semen Quality in Healthy Young Men Living in Highly Polluted Areas in Italy: The FASt Randomized Controlled Trial

Our 4-mo lifestyle intervention with a randomized study design showed that an intervention based on Mediterranean diet and regular physical activity can determine an increase of sperm concentration, total and progressive motility, and proportion of spermatozoa with normal morphology, that is, an increase in total antioxidant capacity in healthy young men. These findings underline the effect of lifestyle factors, particularly dietary habits and physical activity, on sperm quality, and show that moderate lifestyle changes recommended for health promotion and chronic disease prevention can also be helpful for preventing male infertility.