From COVID-19 Infection to social level disease (SLD)

AIM: To analyse, diagnose, and forecast the development of the pandemic Corona disease and to transfer the data into a corresponding virtual ‘orders of structure system’.\r\nBackground: COVID-19 pandemic is a RNA virus transmitted human respiratory tract infection of moderate to high infection rate (20 % – 40 %) and a case fatality ratio of 2 % – 5 %.  The infection rate depends upon age and health condition of exposed persons, density of virus droplets, air temperature, legal regulations as well as social life style and behaviour. \r\nStage of prevention:  The high modulation rate of virus RNA and its protein structure require protective strategies at cellular and macromolecule level (preventive immunization), individual protection (personal risk) such as mouth masks, strict regulations of the social behaviour, shutdown of restaurants, hotels, of travel, public demonstrations, private festivals, etc. Legal regulations often hinder the state and federal government from acting in fully restrictive manner. Numerous citizens are not convinced of the ordered restrictions. They fear severe damage to their ‘freedom’ and economic situation. Therefore, COVID-19 also causes a social level disease (SLD), and should be diagnosed and treated accordingly.\r\nExplanation and diagnosis of a social level disease (SLD):   Nature has organized human life in ordered communicative structures which can be represented by horizontal and vertical coordinates. Horizontally arranged neighbouring structures can often replace damaged or lost structures, in contrast to vertical structures. External interaction, forecast and potential repair of involved structures require statistical algorithms. Calculation of entropy at different structure levels is a useful tool to forecast the disease’s course.\r\nConclusions and advices:  COVID-19 disease is primarily a RNA virus infection which starts at low level structures (macromolecule) and induces alteration of communicative higher order structures. They include primarily pulmonary cells, airways, additional organs, individual persons, human behaviour, profession, trade, organization of societies, states and countries. Severe changes of social behaviour and civil laws are unavoidable consequences. They belong to basic natural laws of communication, droplet distribution, decay of infectious agents and individual protection.