Associations Of Gestational Weight Gain Rate During Different Trimesters With Early-Childhood Body Mass Index And Risk Of Obesity
OBESITY(2020)
摘要
Objective This study aimed to estimate the associations of gestational weight gain rate (GWGR) during different trimesters with offspring growth and overweight/obesity risk. Methods The study included 4,807 mother-infant pairs enrolled in Wuhan, China. GWGR in each trimester was used as a continuous and a categorical variable to estimate the associations with offspring BMIzscore (ZBMI) and overweight/obesity risk between 0 and 2 years. Results Greater GWGR (per 0.2 kg/wk) in the first, second, and third trimester was positively associated with offspring ZBMI across birth to 2 years old (beta 0.06 [95% CI: 0.04-0.09], beta 0.13 [95% CI: 0.09-0.16], and beta 0.04 [95% CI: 0.02-0.07], respectively). Excessive GWGR in the first trimester (>= 0.30 kg/wk) was associated with an odds ratio (OR) of 1.58 (95% CI: 1.18-2.13) and 1.37 (95% CI: 1.11-1.71) for macrosomia and 2-year overweight/obesity, respectively. Excessive GWGR in the second trimester was associated with an OR of 2.09 (95% CI: 1.42-3.08), 1.21 (95% CI: 1.02-1.43), and 1.48 (95% CI: 1.15-1.90) for macrosomia, 1-year, and 2-year overweight/obesity, respectively. Excessive GWGR in the third trimester was associated with an OR of 1.91 (95% CI: 1.27-2.86) and 1.32 (95% CI: 1.02-1.72) for macrosomia and 2-year overweight/obesity, respectively. Conclusions Excessive GWGR in each trimester was positively associated with offspring ZBMI and early-childhood overweight/obesity risk.
更多查看译文
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要