BackgroundThe control of type 1 diabetes mellitus (T1DM) is markedly more difficult for adolescents, with this age group typically displaying higher HbA1c values than earlier or later age groups. Poor control is due in part to the omission of insulin for carbohydrates ingested at snacks and meals, both in the form of missing boluses entirely and underestimating carbohydrate content and thus the dosage of insulin required. The study hypothesized that AP systems would alleviate high blood glucose (BG) in adolescents in the setting of missed boluses at snacks and underestimated boluses at mealtimes and would thus offer a possible way to improve the management of T1DM for adolescents.MethodsThe randomized cross-over trial enrolled 16 adolescents with T1DM, aged 13 to 18 years old, who had been using an insulin pump for six or more months and self-reported a history of missing insulin or underbolusing. On …
