Diabetes And Its Predictive Role In The Incidence Of Alzheimer'S Disease

Introduction: Diabetes is the fifth cause of death in most countries of the world and Causing disability, high cost of treatment and increased mortality. Some studies indicate that one of these complications of diabetes is the development of Alzheimer's disease. So this study was done to the aim of determine the predictive role of diabetes in the development of Alzheimer's disease in diabetic patients admitted to hospitals Three cities from Khuzestan province. Materials and methods: This study is a retrospective cross-sectional analytical descriptive study. The study included a survey of 1855 cases of diabetes patients admitted to hospitals in Shoushtar, Behbahan, and Abadan, which was conducted by eight investigators. The records of these patients diagnosed with diabetes and referring to medical centers in the mentioned cities during 2015-2017, which were extracted from medical records of city hospitals and entered the study. The data in this study included demographic, laboratory and clinical data of patients. Then, Data were entered into SPSS software version 17 and analyzed by descriptive statistics, analytical tests and significant level of P < 0.05. Results: The study included 1855 individuals with diabetes with an average age of 57.00 +/- 46.23 years. Of these, 1122 (60.4%) were female and the rest were male. In terms of job, the highest percentage was related to free employment with 653 people (35.2%). In this study, 258 (13.9%) of those with diabetes also had Alzheimer's disease. And a statistically significant relationship was found between jobs with those with Alzheimer's disease (0.003). There was a significant relationship between diabetes and those with Alzheimer's disease (p = 0.006). But there was no significant relationship between diabetes and those with a history of cardiovascular disease (p = 0.09). Conclusion: In this study, there was a significant relationship between diabetes and those with Alzheimer's disease. Therefore, this study showed the risk of Alzheimer's disease in diabetic patients in the three counties. Therefore, follow-up is needed to prevent diabetes. And measures to change lifestyles, such as the use of aerobic exercise, a healthy diet should be done. Also, regular referral to the Doctor should be done in these patients.