Risk Factors And Management Of Postoperative Infection Following Cochlear Implantation

OTOLOGY & NEUROTOLOGY(2020)

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摘要
Objective: To determine factors associated with infection, management, and resultant outcomes following pediatric cochlear implantation.Study Design: Retrospective cohort study with nested case series.Setting: Tertiary academic medical center.Patients: Children who underwent either unilateral or bilateral cochlear implantation between June 2011 and September 2016 and were under the age of 18 at the time of surgery.Intervention(s): Subjects were compared based on age, cochlea malformation, revision surgery, operative time, device manufacturer, and antibiotic use. Infections were compared based on location, time, bacteria, management, and resolution.Main Outcome Measure(s): Rate of infection, rate of device explantation.Results: There were 16 infections among 246 surgeries, an infection rate of 6.5%. There was a significant age difference between infected and noninfected patients overall (n = 246, 1.4 versus 4.3 years, p = 0.005), but not within the cohort of patients five or younger (n = 172, 1.4 versus 1.8 years, p = 0.363). The most common infectious complication was skin infection, followed by device infection. No cases of meningitis were seen. The most common organism was S Aureus. The implant was salvaged in 9 of 16 patients (56.3%), with higher rates in patients treated with IV versus oral antibiotics (70 versus 40%).Conclusions: Postoperative infection is positively associated with younger age overall, but not in patients below the age of 5. With modern devices and surgical practices, risk of meningitis-though a concern-may be lower than cited in the literature. Prompt and aggressive therapy with IV antibiotics and operative intervention can allow for high rates of device salvage.
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关键词
CI, Cochlear implant, Complication, Infection, Meningitis, Pediatric
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