Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652, a Reversible Fatty Acid Amide Hydrolase Inhibitor, in Healthy, Nonelderly, Japanese Men and Elderly, Japanese Men and Women: A Randomized, Double-blind, Placebo-controlled, Single and Multiple Oral Dose, Phase I Study.
Clinical Therapeutics（2020）
摘要
Single and multiple doses of ASP3652 were well tolerated and increased endogenous cannabinoids.
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关键词
anandamide,fatty acid amide hydrolase,healthy Japanese patients,pharmacokinetics,phase I,tolerability
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