Modeling the transmission of the new coronavirus in São Paulo State, Brazil—assessing the epidemiological impacts of isolating young and elder persons

We developed a mathematical model to describe the new coronavirus transmission in São Paulo State, Brazil. The model divided a community into subpopulations composed of young and elder persons considering a higher risk of fatality among elder persons with severe CoViD-19. From the data collected in São Paulo State, we estimated the transmission and additional mortality rates. Based on the estimated model parameters, we calculated the basic reproduction number $R_{0}$ , and we retrieved the number of deaths due to CoViD-19, which was three times lower than those found in the literature. Considering isolation as a control mechanism, we varied the isolation rates in the young and elder subpopulations to assess the epidemiological impacts. The epidemiological scenarios focused mainly on evaluating the reduction in the number of severe CoViD-19 cases and deaths due to this disease when isolation is introduced in a population.