Early epidemiological and clinical characteristics of 28 cases of coronavirus disease in South Korea

Insik Kong,Youngjoon Park,Yeonhee Woo,Joosun Lee,Jeongok Cha, Junkil Choi,Youngman Kim,Jieun Kim, Shinyoung Park, Minwoo Yum,Taeyoung Kim,Joongho Jo,Miyoung Kim,Donghan Lee, Jonghee Kim,Sookkyung Park,Hyunjung Bahk, Jeonghee Yu,Jeongran Kwon, Heesook Kim, Nari Shin, Sanghyuk Lee, Hyekyung In, Jangeun Jung,Seunghee Cho,Byounghak Jeon,Dongwook Kim,Gwack Jin,Seongsun Kim,Sungnam Kim, Youngki Kim,Eunyoung Kim, Byran Inho Kim, Heejung Kim,Hyeyoung Lee,Yeowon Jin, Jeonghyun Kim, Hwami Kim,Boyeong Ryu,Seunghwan Shin,Eensuk Shin,Jin Lee,Sangeun Lee, Yoonsuk Jang,Eunkyung Choi,Junghee Hyun,Daehyeon Ko, Garam Seo, Seunghwi Kwon,Eunmi Park,Seungwoo Choi, Seondo Hwang, Byunghak Kang, Jaesun Park,Deogyong Lee, Sukyoung Jo,Siwon Choi,Junghyun Lee, Sanghyun Cho, Jaekyung Park, Junnyun Kim, Eungyu Lee, Jungsook Kim,Sunmi Kim,Unna Kim

Osong public health and research perspectives(2020)

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摘要
Objectives: The first confirmed case of coronavirus disease 2019 (COVID-19) in South Korea was reported in January 2020, with 28 confirmed cases reported as of February 14th, 2020. The epidemiological and clinical characteristics of all 28 cases were analyzed in response to this disease. Methods: The epidemiological characteristics and early clinical features of the 28 patients from Korea with confirmed COVID-19 were analyzed using COVID-19 reporting and surveillance data and the epidemiological investigation reports prepared by the rapid response team. Results: There were 16 patients that entered Korea from foreign countries: Wuhan, China (11 patients), Zhuhai, China, (1 patient), Singapore (2 patients), Japan (1 patient), and Thailand (1 patient). The early symptoms were fever, sore throat, cough or sputum production, chills, and muscle ache. Three patients were asymptomatic, however, 18 developed pneumonia. Of the 28 cases, 16 were index cases imported from abroad, with 10 cases of secondary infection originating in Korea, and the route of transmission still under investigation for 2 patients. The 10 patients with secondary infection were infected from contact with family members or acquaintances of primary patients, and the suspected sites of transmission were mostly at home. Conclusion: COVID-19 in Korea was spread by 16 infected individuals traveling from other countries, leading to second-generation cases. The initial symptoms were mostly minor, but the disease was infectious at this stage, resulting from close contact, particularly at home. Establishing an early detection strategy for COVID-19 is crucial for managing the transmission of the disease.
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COVID-19, epidemiologic study, SARS-CoV-2
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