Numerical Modeling of Glucose Biosensor With pH-Based Electrochemical Field-Effect Transistor Device
IEEE Transactions on Electron Devices(2020)
摘要
In this article, we present a new model for glucose detection using an electrochemical field-effect transistor (ElecFET) with the MATLAB software. ElecFET is a device in which the basic element is a pH-sensitive chemical field-effect transistor (pH-ChemFET) designed with an integrated platinum microelectrode around the sensitive gate dielectric capable to trigger electrochemical reactions. A number of parameters, such as polarization time (
${T}_{\text {pol}}$
) and polarization voltage (
${V}_{p}$
), have been investigated, as well as the enzymatic unit number per volume (
${N}_{\text {enz}}$
), the Michaelis constant (
${K}_{M}$
), and the glucose concentration (
${C}_{{0}}$
). Each of the aforementioned parameters influences the glucose sensor response. Experimental data compared with our numerical model showed a reasonable fit.
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关键词
Sugar,Mathematical model,Microelectrodes,Ions,Biosensors,Hydrogen,Numerical models
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